in process …


Something bad happened. You should try to fix …


The action is completed.

Is a hereditary disorder of the connective tissue related

The content of the website and databases of the National Organization for Rare Disorders (NORD) is copyrighted and may not be reproduced, copied, downloaded or disseminated, in any way, for any commercial or public purpose, without prior written authorization and approval from NORD. Individuals may print one hard copy of an individual disease for personal use, provided that content is unmodified and includes NORD’s copyright.

Abnormal proliferation and differentiation of connective tissue cells called fibroblasts are important in the development of . The palmar fascia of people with this disorder has an excess of myofibroblasts, which are a type of fibroblast containing protein strands called myofibrils. Myofibrils normally form the basic unit of muscle fibers, allowing them to contract. The increased number of myofibroblasts in this disorder cause abnormal contraction of the fascia and produce excess amounts of a connective tis

The resources on this site should not be used as a substitute for professional medical care or advice. Users with questions about a personal health condition should consult with a .

This makes it very important people with Marfan syndrome and related disorders to receive accurate, early diagnosis and treatment. Without it, they can be at risk for potentially life-threatening complications. The earlier some treatments are started, the better the outcomes are likely to be.

Your contribution may be further edited by our staff, and its publication is subject to our final approval. Unfortunately, our editorial approach may not be able to accommodate all contributions. Our editors will review what you’ve submitted and determine whether to revise the article.

Related links


exce called type fascia content