Increasing glutathione concentration is the main treatment goal in relation to the methionine and transsulfuration pathways. Previously it was determined that oral glutathione supplements were not well absorbed therefore other alternatives were studied . Since cysteine is the rate–limiting factor in glutathione synthesis, a precursor form of glutathione is now used and offers improved efficacy. N–acetylcysteine has beneficial effects in glutathione levels and autistic behaviors [11,28]. Auti
29. James SJ, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, et al. Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. (2009) 89(1):425–30. doi:10.3945/ajcn.2008.26615The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
A total of 69 children were recruited. Of these, 38 had a diagnosis of ASD (29 males and 9 females) and 31 were classified as typically developing (TD) children (23 males and 8 females)
The answer is rarely one thing it is usually a combination of some or all of the following:Researchers have recently made great gains in the understanding of biomedical causes of speech and language issue, as: