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A test of the neurogenic hypothesis of infantile amnesia. Memory persistence is inversely correlated with levels of neurogenesis. Our hypothesis is that infants cannot form long-lasting memories because of high levels of neurogenesis, which promotes forgetting of recently acquired memories. We predict that making the hippocampus of an otherwise adult mouse “infantile” (increasing neurogenesis, solid black arrow) should promote forgetting of already acquired memories. On the other hand, making the hippoc

In a Bayesian point-null hypothesis test, the null hypothesis is expressed as a prior distribution that puts all credibility in an infinitely dense spike at the null value of the parameter, with zero credibility on all other values of that parameter. In other words, the prior distribution for the null hypothesis says that only the null value is available. (The Bayesian framework allows other types of null hypotheses, but here we focus on point nulls for comparability to NHST.) Crucially, the null hypothesis

One model in particular, the “Oxygen and capacity limited thermal tolerance (OCLTT) model”, has gained wide acceptance and is currently used in forecasting the effects of climate change on species distributions and future performance. This model, based on the work of Fry and Hart, proposes that cardiorespiratory system failure is the principal determinant of both upper critical temperature where animals lose equilibrium (Tcrit), and the realized environmental thermal niche. Under the OCLTT framework, th

The direct cause, or causes, of are unknown. Even though no consensus exists for the causes of Asperger&aposs syndrome, it is widely accepted that Asperger&aposs syndrome has a hereditary factor. It is suspected that multiple genes play a part in causing Asperger syndrome, since the number and severity of symptoms vary widely among individuals.